Genetika člověka
Mikrobiologické aplikace
NGS
Rapid testy
PCR plasty
Pipetovací špičky
Plasty pro buněčnou kultivaci
Systém pro dlouhodobé skladování vzorků
Zkumavky
Třepačky
Suché lázně
Centrifugy
End Point cyclery
Real-time PCR cyclery
Fluorometry
Spektrofotometry
Izolátory nukleových kyselin
Pipetovací roboty
Biobanking
Live Cell Imaging
Jednokanálové
Multikanálové
Sérologické pipety
Jednorázové pipety
Buněčné kultury
PCR, qPCR, RT
Detekce Mycoplasmat
Reverzní transkripce
Alergie
Intolerance
Elisa
Imunologické analyzátory
Veterinární imunologie
Alergie u zvířat
Intolerance u zvířat
Biochemie
Imunoanalýza
HCC 3-4 Cells
| Unit |
1×10⁶ cells / 1.0 ml |
|---|---|
| Cell Type |
Tumor Cells |
| Tissue Type |
Liver |
| Organism |
Mouse (M. musculus) |
| Donor History |
LAP-tTA/TRE-MYC transgenic mice ,Hepatocellular carcinoma |
| Growth Properties |
Adherent ,polygonal |
| Growth Conditions |
Use of PriCoat™ T25 Flasks (G299) or Applied Cell Extracellular Matrix (G422) is required for cell adhesion to the culture vessels. PriGrow III (TM003) + 10% FBS + 1% Penicillin/Streptomycin Solution (G255) ,37.0°C ,5% CO₂ |
| Immortalization Method |
Tumor Cell Line |
| Full Information |
Hepatocellular carcinoma (HCC) is one of the most common and incurable malignancies. It is strongly associated with hepatitis B and hepatitis C virus infection, which leads to the activation of oncogenes including MYC. MYC is highly involved in tumorigenesis and thus inactivation of MYC may provide an effective therapy for HCC. The HCC 3-4 Cells are generated to have controllable MYC expression. The cells are dependent upon high levels of human MYC expression, which can be inactivated upon treatment with Dox.
