Human IFNAR1 Stable Knockout HeLa Cell Line

Unit

1×10⁶ cells / 1.0 ml

Cell Type

Stable (KO/Expressing) Cells

Tissue Type

Cervix

Organism

Human (H. sapiens)

Donor History

Growth Properties

Adherent

epithelial

Growth Conditions

PriCoat™ T25 Flasks (G299) or Applied Cell Extracellular Matrix (G422) are recommended for optimal cell culture. Dulbecco's Modified Eagle Medium (DMEM)

High Glucose (TM500) + 10% FBS + 1 mM Sodium Pyruvate (TM057) + 1% Penicillin/Streptomycin Solution (G255)

37.0°C

5% CO₂.

Immortalization Method

Full Information

https://www.abmgood.com/Human-IFNAR1-Stable-Knockout-HeLa-Cell-Line-T3980.html

The Human IFNAR1 Stable Knockout HeLa Cell Line (T3980) features a stable knockout of the IFNAR1 gene, crucial for Type I interferon signaling. This cell line, derived from the HeLa cervical cancer cell line, serves as a vital tool for dissecting the complex pathways involved in the innate and adaptive immune responses. The knockout of IFNAR1 abrogates Type I interferon-induced signaling, thereby preventing the activation of JAK-STAT pathways and the subsequent expression of interferon-stimulated genes (ISGs). It is instrumental in studying the role of IFNAR1 in mediating antiviral responses, understanding the mechanism of interferon-induced gene regulation, and exploring the therapeutic potential of targeting interferon pathways in diseases.Complete list of cell lines from this panel:Cat. T3980 – Human IFNAR1 Stable Knockout HeLa Cell LineCat. T3981 – Human IFNAR2 Stable Knockout HeLa Cell LineCat. T3982 – Human STAT1 Stable Knockout HeLa Cell LineCat. T3983 – Human STAT2 Stable Knockout HeLa Cell Line

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Unit	1×10⁶ cells / 1.0 ml
Cell Type	Stable (KO/Expressing) Cells
Tissue Type	Cervix
Organism	Human (H. sapiens)
Donor History
Growth Properties	Adherent , epithelial
Growth Conditions	PriCoat™ T25 Flasks (G299) or Applied Cell Extracellular Matrix (G422) are recommended for optimal cell culture. Dulbecco's Modified Eagle Medium (DMEM) , High Glucose (TM500) + 10% FBS + 1 mM Sodium Pyruvate (TM057) + 1% Penicillin/Streptomycin Solution (G255) , 37.0°C , 5% CO₂.
Immortalization Method
Full Information	https://www.abmgood.com/Human-IFNAR1-Stable-Knockout-HeLa-Cell-Line-T3980.html

Přidat mezi Oblíbené

Katalogové číslo: T3980 Kategorie: Buněčné linie, Stable (KO/Expression) Cell Lines

Popis
O značce

Popis

O značce

Applied Biological Materials (abm) je jedním z našich klíčových dodavatelů pro biotechnologický průmysl. Společnost byla založena v roce 2004 a již více než deset let podporuje vědecké objevy v oblasti přírodních věd a vývoje léčiv. Její sídlo se nachází ve Vancouveru v Kanadě. ABM je pro nás neocenitelným partnerem zejména v  oblasti dodávek buněčných kultur, genových a virových vektorů, produktů pro molekulární biologii a PCR, nástrojů pro technologie CRISPR a RNAi, protilátek i základních reagencií pro molekulárně genetické procesy.

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