KLN-205 Cells
| Unit |
3 x 10^6 cells/ml |
|---|---|
| Cell Type |
Tumor Cells |
| Tissue Type |
Mouse cell lines |
| Organism |
Mouse |
| Donor History |
Squamous cell carcinoma |
| Growth Properties |
Adherent |
| Growth Conditions |
Culture medium: EMEM (MEM Eagle) ,w: 2 mM L-Glutamine ,w: 2.2 g/L NaHCO3 ,w: EBSS (Cytion article number 820100a). Supplements: Supplement the medium with 10% FBS and 1% NEAA. Dissociation reagent: Accutase. Freeze medium: As a cryopreservation medium ,we use complete growth medium (including FBS) + 10% DMSO for adequate post-thaw viability ,or CM-1 (Cytion catalog number 800100) ,which includes optimized osmoprotectants and metabolic stabilizers to enhance recovery and reduce cryo-induced stress. Incubation atmosphere: 37°C ,5% CO2 ,humidified atmosphere. |
| Immortalization Method | |
| Full Information |
KLN-205 is a murine lung carcinoma cell line derived from an adult mouse. This cell line is widely used in cancer research, particularly for studying the mechanisms of lung cancer progression, metastasis, and potential therapeutic interventions. KLN-205 cells exhibit characteristics typical of non-small cell lung carcinoma (NSCLC), making them a valuable model for investigating the molecular and cellular underpinnings of this disease. Researchers utilize KLN-205 to evaluate the efficacy of various chemotherapeutic agents, immunotherapies, and targeted treatments, helping to advance the understanding of lung cancer biology and treatment strategies.
KLN-205 cells are known for their robust growth and ability to form tumors when implanted in immunocompromised mice, providing a reliable in vivo model for preclinical studies. These cells are used to explore tumor-host interactions, immune responses to lung cancer, and the impact of genetic and epigenetic modifications on cancer development and progression. The KLN-205 cell line serves as a critical tool in oncology research, aiding in the identification of novel biomarkers and therapeutic targets for lung cancer.
Společnost Cytion vznikla v roce 2004 v německém Heidelbergu s jasným vědeckým posláním: dodávat ověřené lidské a zvířecí buněčné linie bez kontaminace, připravené za přísně kontrolovaných laboratorních podmínek.
Postupně se vypracovala ve spolehlivou buněčnou banku, která slouží akademickým laboratořím, biotechnologickým firmám i farmaceutickým výzkumným týmům po celém světě. Klade přitom důraz na reprodukovatelnost výsledků, přísnou kontrolu kvality a dlouhodobá partnerství.
Mikrobiologické aplikace
NGS
Rapid testy
PCR plasty
Třepačky
Suché lázně
Fluorometry
Buněčné kultury
PCR, qPCR, RT
Detekce Mycoplasmat
Reverzní transkripce
Alergie
Intolerance
Elisa
Imunologické analyzátory
Veterinární imunologie
Alergie u zvířat
Intolerance u zvířat
Čtečky identifikačních čipů
Termočipy
Biochemie
Imunoanalýza

