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MRG15 (Mouse) CRISPR Knock Out MEF Cell Line
| Unit |
1×10⁶ cells / 1.0 ml |
|---|---|
| Cell Type |
Stable (KO/Expressing) Cells |
| Tissue Type |
Embryo |
| Organism |
Mouse (M. musculus) |
| Donor History | |
| Growth Properties |
Adherent ,fibroblast |
| Growth Conditions |
PriCoat™ T25 Flasks (G299) or Applied Cell Extracellular Matrix (G422) are recommended for optimal cell culture. Dulbecco's Modified Eagle Medium (DMEM) ,High Glucose (TM500) + 10% FBS + 1% Penicillin/Streptomycin Solution (G255) ,37.0°C ,5% CO₂. |
| Immortalization Method | |
| Full Information |
https://www.abmgood.com/MRG15-Mouse-CRISPR-Knock-Out-MEF-Cell-Line-T9830.html |
The MRG15 (Mouse) CRISPR Knock Out MEF Cell Line was generated using CRISPR-Cas9 technology and features a targeted knockout of the MRG15 gene in mouse embryonic fibroblasts (MEFs). MRG15 is a critical component of chromatin remodeling complexes and is involved in regulating gene expression, DNA repair, and cell cycle progression. By studying the effects of MRG15 deletion, researchers can gain insights into its role in epigenetic regulation, the aging process, and the maintenance of genomic integrity. This cell line is invaluable for uncovering the molecular pathways governed by MRG15, offering potential targets for therapeutic intervention in aging-related diseases and cancer.
