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NTCP Stable Expressing Huh7 Cell Line
| Unit |
1×10⁶ cells / 1 ml |
|---|---|
| Cell Type |
Stable (KO/Expressing) Cells |
| Tissue Type |
Liver |
| Organism |
Human (H. sapiens) |
| Donor History |
Male ,57 ,Asian ,Adult hepatocellular carcinoma |
| Growth Properties |
Adherent ,polygonal |
| Growth Conditions |
PriCoat™ T25 Flasks (G299) or Applied Cell Extracellular Matrix (G422) are recommended for optimal cell culture. Dulbecco's Modified Eagle Medium (DMEM) ,High Glucose (TM500) + 10% FBS + 1X Non-Essential Amino Acids (TM068) + 1% Penicillin/Streptomycin Solution (G255) ,37.0°C ,5% CO₂. |
| Immortalization Method | |
| Full Information |
https://www.abmgood.com/ntcp-stable-expressing-huh7-cell-line.html |
NTCP Stable Expressing Huh7 Cell Line stably expresses the Hepatitis B virus (HBV) receptor, sodium taurocholate co-transporting polypeptide (NTCP). Although there is an effective vaccine for HBV, there is currently no effective and affordable treatment regimen. NTCP has been shown to be the main factor controlling host specificity and hepatotropism of HPV at the entry level. Knockdown studies of NTCP in infection susceptible cells significantly reduced the infection rate and over-expressing NTCP in previously infection non-permissive cells rendered them susceptible to HBV infection. NTCP Stable Expressing Huh7 Cell Line is a useful model for future studies of the HBV virus.
