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Prothrombin Mutant (R393Q) Stable Expressing HEK293 Cell Line
| Unit |
1×10⁶ cells / 1 ml |
|---|---|
| Cell Type |
Stable (KO/Expressing) Cells |
| Tissue Type |
Kidney |
| Organism |
Human (H. sapiens) |
| Donor History |
Embryo |
| Growth Properties |
Adherent ,epithelial |
| Growth Conditions |
PriCoat™ T25 Flasks (G299) or Applied Cell Extracellular Matrix (G422) are recommended for optimal cell culture. Dulbecco's Modified Eagle Medium (DMEM) ,High Glucose (TM500) + 10% FBS + 1% Penicillin/Streptomycin Solution (G255) ,37.0°C ,5% CO₂. |
| Immortalization Method | |
| Full Information |
https://www.abmgood.com/prothrombin-mutant-r393q-stable-expressing-hek293-cell-line.html |
Mannan-binding lectin-associated serine protease-1 (MASP-1) is a protein of the lectin pathway. Its similar in terms of structural features and substrate specificity to thrombin. Via its ability to induce fibrin clot formation along with interplay with several coagulation factors, MASP-1 has been shown to activate prothrombin. With the Prothrombin Mutant (R393Q) Stable Expressing HEK293 Cell Line, you can investigate in detail the mechanism of MASP-1 in mediating prothrombin activation.
