Genetika člověka
Mikrobiologické aplikace
NGS
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PCR plasty
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PCR, qPCR, RT
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Veterinární imunologie
Alergie u zvířat
Intolerance u zvířat
Biochemie
Imunoanalýza
Human GLA Stable Knockout HEK293 Cell Line
| Unit |
1×10⁶ cells / 1.0 ml |
|---|---|
| Cell Type |
Stable (KO/Expressing) Cells |
| Tissue Type |
Kidney |
| Organism |
Human (H. sapiens) |
| Donor History | |
| Growth Properties |
Adherent ,epithelial |
| Growth Conditions |
PriCoat™ ECM T25 Flasks (G999) or Applied Cell Extracellular Matrix (G422) are required for cell adhesion to the culture vessels. Dulbecco's Modified Eagle Medium (DMEM) ,High Glucose (TM500) + 10% FBS + 1% Penicillin/Streptomycin Solution (G255) ,37.0°C ,5% CO₂. |
| Immortalization Method | |
| Full Information |
https://www.abmgood.com/Human-GLA-Stable-Knockout-HEK293-Cell-Line-T3398.html |
This cell line (Cat. T3398) features a stable knockout of the GLA gene through CRISPR/Cas9 genome editing. NGS was used to verify exon deletion. This cell line is suitable for the study of GLA gene functions, related metabolic pathways, and the pathogenesis of Fabry disease. It provides a valuable model for drug screening, understanding GLA-related enzyme activity, and exploring potential therapeutic interventions for disorders associated with GLA gene.
