Genetika člověka
Mikrobiologické aplikace
NGS
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Jednokanálové
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PCR, qPCR, RT
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Reverzní transkripce
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Intolerance
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Imunologické analyzátory
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Alergie u zvířat
Intolerance u zvířat
Biochemie
Imunoanalýza
COS-7-DRA1*01:01/DRB5*01:01 Cell Line
| Unit |
1×10⁶ cells / 1.0 ml |
|---|---|
| Cell Type |
Stable (KO/Expressing) Cells |
| Tissue Type |
Kidney |
| Organism |
Monkey (Primate) |
| Donor History |
Cercopithecus aethiops |
| Growth Properties |
Adherent ,fibroblast |
| Growth Conditions |
PriCoat™ T25 Flasks (G299) or Applied Cell Extracellular Matrix (G422) are recommended for optimal cell culture. Dulbecco's Modified Eagle Medium (DMEM) ,High Glucose (TM500) + 10% FBS + 2 mM L-Glutamine (G275) + 1% Penicillin/Streptomycin Solution (G255) ,37.0°C ,5% CO₂. |
| Immortalization Method | |
| Full Information |
The COS-7-DRA101:01/DRB501:01 cell line expresses the HLA-DRA101:01 and DRB501:01 antigens, which play critical roles in immune recognition and T-cell activation. Engineered via retroviral transduction and validated using flow cytometry, this cell line is maintained without antibiotics. It is valuable for studying the interactions between HLA class II molecules and helper T-cells, providing insights into autoimmune diseases and vaccine development.
