Canine Lymph Node Metastasis TCC Cell Line (KU-CTCC-001-LM3)

Unit

1×10⁶ cells / 1.0 ml

Cell Type

Tumor Cells

Tissue Type

Lymph Node

Organism

Dog (Canine)

Donor History

Jindo

Transitional Cell Carcinoma

Growth Properties

Adherent

round to spindle

Growth Conditions

PriCoat™ T25 Flasks (G299) or Applied Cell Extracellular Matrix (G422) are recommended for optimal cell culture. PriGrow X Series Medium for T8167 (TM8167) + 10% FBS + 10 mM HEPES + 1X GlutaMAX 1% Penicillin/Streptomycin Solution (G255)

37.0°C

5% CO₂.

Immortalization Method

Tumor Cell Line

Full Information

https://www.abmgood.com/Canine-Lymph-Node-Metastasis-TCC-Cell-Line-KU-CTCC-001-LM3-T8167.html

KU-CTCC-001-LM3, established from a metastatic lymph node of the same patient as KU-CTCC-001 (Cat. T8165), harbors the BRAF V595E mutation and displays activated MAPK signaling. This cell line presents a unique model to study metastatic processes, offering insights into the molecular and cellular mechanisms underlying TCC spread. Its growth characteristics and sensitivity to BRAF inhibitors, including a notable response to sorafenib, make it a critical tool for advancing understanding of metastasis, evaluating therapeutic strategies for metastatic disease, and contributing to the development of personalized medicine approaches in canine and human oncology.Note: KU-CTCC-001-LM3, derived from a metastatic site, enables focused research on the metastatic behavior and potential therapeutic targets specific to TCC metastasis, compared to KU-CTCC-001 (Cat.T8165) and KU-CTCC-002 (Cat.T8166), which are derived from primary tumors. Its slightly slower proliferation rate in vitro versus KU-CTCC-001 (Cat. T8165) might reflect differences in growth dynamics between primary and metastatic cancer cells.Complete list of cell lines from this panel:Cat. T8165 – Canine Transitional Cell Carcinoma Cell Line (KU-CTCC-001)Cat. T8166 – Canine Transitional Cell Carcinoma Cell Line (KU-CTCC-002)Cat. T8167 – Canine Lymph Node Metastasis TCC Cell Line (KU-CTCC-001-LM3)

Click to enlarge

Unit	1×10⁶ cells / 1.0 ml
Cell Type	Tumor Cells
Tissue Type	Lymph Node
Organism	Dog (Canine)
Donor History	10 , Jindo , Transitional Cell Carcinoma
Growth Properties	Adherent , round to spindle
Growth Conditions	PriCoat™ T25 Flasks (G299) or Applied Cell Extracellular Matrix (G422) are recommended for optimal cell culture. PriGrow X Series Medium for T8167 (TM8167) + 10% FBS + 10 mM HEPES + 1X GlutaMAX 1% Penicillin/Streptomycin Solution (G255) , 37.0°C , 5% CO₂.
Immortalization Method	Tumor Cell Line
Full Information	https://www.abmgood.com/Canine-Lymph-Node-Metastasis-TCC-Cell-Line-KU-CTCC-001-LM3-T8167.html

Přidat mezi Oblíbené

Katalogové číslo: T8167 Kategorie: Buněčné linie, Tumor Cell Lines

Popis
O značce

Popis

O značce

Applied Biological Materials (abm) je jedním z našich klíčových dodavatelů pro biotechnologický průmysl. Společnost byla založena v roce 2004 a již více než deset let podporuje vědecké objevy v oblasti přírodních věd a vývoje léčiv. Její sídlo se nachází ve Vancouveru v Kanadě. ABM je pro nás neocenitelným partnerem zejména v  oblasti dodávek buněčných kultur, genových a virových vektorů, produktů pro molekulární biologii a PCR, nástrojů pro technologie CRISPR a RNAi, protilátek i základních reagencií pro molekulárně genetické procesy.

Canine Lymph Node Metastasis TCC Cell Line (KU-CTCC-001-LM3)

Ampullary Neuroendocrine Carcinoma Cell Line (NEC1452)

HMC-1.3 Mast Cell Line (Clone 2E2)

Human Hematopoietic‐Myeloid Leukemia Cell Line (AML14.3D10)

MKN28 Cells

Vero Cell Line (Animal Component Free)

VM-NM1 Cells

WSU-DLCL Cells

Y-1 Cells

Canine Lymph Node Metastasis TCC Cell Line (KU-CTCC-001-LM3)

Související produkty