DU4475 Cells

Unit

5 x 10^6 cells/ml

Cell Type

Tumor Cells

Tissue Type

Breast cancer cell lines

Organism

Human

Donor History

Breast carcinoma

Growth Properties

Clusters in Suspension

Growth Conditions

Culture medium: RPMI 1640

,

w: 2.0 mM stable Glutamine

,

w: 2.0 g/L NaHCO3 (Cytion article number 820700a). Supplements: Supplement the medium with 15% heat-inactivated FBS. Freeze medium: As a cryopreservation medium

,

we use complete growth medium (including FBS) + 10% DMSO for adequate post-thaw viability

,

or CM-1 (Cytion catalog number 800100)

,

which includes optimized osmoprotectants and metabolic stabilizers to enhance recovery and reduce cryo-induced stress. Incubation atmosphere: 37°C

,

5% CO2

,

humidified atmosphere.

Immortalization Method
Full Information

https://www.cytion.com/DU4475-Cells/300371

SKU: 300371 Kategorie: ,
Mgr. Otakar Fišer
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Mgr. Otakar Fišer
Produktový manažer - Life Science
Popis

The DU4475 cell line is a human breast cancer cell line derived from a metastatic site. It is characterized by its aggressive nature and poor differentiation, often used in research to study the mechanisms of cancer metastasis and progression. The cell line has been utilized extensively to explore the therapeutic targets and the efficacy of anti-cancer drugs in treating highly invasive breast cancer types.

Genetically, DU4475 exhibits a high level of genetic instability, which is a hallmark of many cancer cells. This feature makes it a valuable model for studying the genetic and molecular events leading to cancer development and progression. Research involving DU4475 often focuses on the pathways that regulate cancer cell growth, survival, and resistance to chemotherapy, making it a critical resource for oncological studies aiming to develop more effective cancer treatments.

O značce

Společnost Cytion vznikla v roce 2004 v německém Heidelbergu s jasným vědeckým posláním: dodávat ověřené lidské a zvířecí buněčné linie bez kontaminace, připravené za přísně kontrolovaných laboratorních podmínek.

Postupně se vypracovala ve spolehlivou buněčnou banku, která slouží akademickým laboratořím, biotechnologickým firmám i farmaceutickým výzkumným týmům po celém světě. Klade přitom důraz na reprodukovatelnost výsledků, přísnou kontrolu kvality a dlouhodobá partnerství.