HBZY-1 Cells

Unit

3 x 10^6 cells/ml

Cell Type

Immortalized Cells

Tissue Type

Rat cell lines

Organism

Rat

Donor History
Growth Properties

Adherent

Growth Conditions

Culture medium: DMEM

,

w: 4.5 g/L Glucose

,

w: 4 mM L-Glutamine

,

w: 3.7 g/L NaHCO3

,

w: 1.0 mM Sodium pyruvate (Cytion article number 820300a). Supplements: Supplement the medium with 10% FBS. Dissociation reagent: Accutase. Freeze medium: As a cryopreservation medium

,

we use complete growth medium (including FBS) + 10% DMSO for adequate post-thaw viability

,

or CM-1 (Cytion catalog number 800100)

,

which includes optimized osmoprotectants and metabolic stabilizers to enhance recovery and reduce cryo-induced stress. Incubation atmosphere: 37°C

,

5% CO2

,

humidified atmosphere.

Immortalization Method
Full Information

https://www.cytion.com/HBZY-1-Cells/305206

SKU: 305206 Kategorie: ,
Mgr. Otakar Fišer
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Mgr. Otakar Fišer
Produktový manažer - Life Science
Popis

HBZY-1 cells are primary cells isolated from the glomerulus of rat kidneys, specifically from mesangial cells. These cells are highly regarded in scientific research due to their origin and functionality. The glomerulus, a key structure in the kidney, is crucial for blood filtration and purification. Mesangial cells play a significant role in maintaining the structure and function of this specialized renal unit. Thus, HBZY-1 cells provide a valuable model for studying the intricacies of renal biology and advancing our understanding of kidney-related diseases.
Employed in various scientific studies, HBZY-1 cells allow researchers to delve into mesangial cell function and the pathogenesis of kidney diseases. This makes them an essential tool for investigating cellular processes, signaling pathways, and molecular interactions that are pivotal in renal biology. Utilizing these cells in vitro offers insights into the molecular mechanisms governing mesangial cell behavior, enhancing our knowledge of their role in kidney function and disease.
Furthermore, HBZY-1 cells are utilized in pathophysiological studies of kidney diseases, such as glomerulonephritis and diabetic nephropathy. These cells can be subjected to experimental conditions that mimic disease states, providing a platform to study the molecular events that contribute to renal pathology. This capacity makes HBZY-1 cells instrumental in drug discovery and the development of therapeutic interventions aimed at treating kidney-related disorders, potentially leading to significant advancements in patient care and treatment strategies.

O značce

Společnost Cytion vznikla v roce 2004 v německém Heidelbergu s jasným vědeckým posláním: dodávat ověřené lidské a zvířecí buněčné linie bez kontaminace, připravené za přísně kontrolovaných laboratorních podmínek.

Postupně se vypracovala ve spolehlivou buněčnou banku, která slouží akademickým laboratořím, biotechnologickým firmám i farmaceutickým výzkumným týmům po celém světě. Klade přitom důraz na reprodukovatelnost výsledků, přísnou kontrolu kvality a dlouhodobá partnerství.