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Imunoanalýza
Immortalized Mouse Leptin Receptor-deficient Macrophage Cells (DB-1)
| Unit |
1×10⁶ cells / 1.0 ml |
|---|---|
| Cell Type |
Immortalized Cells |
| Tissue Type |
Bone Marrow |
| Organism |
Mouse (M. musculus) |
| Donor History |
Leptin receptor-deficient mouse (db/db) ,male |
| Growth Properties |
Adherent ,polygonal |
| Growth Conditions | |
| Immortalization Method |
Spontaneous immortalization |
| Full Information |
https://www.abmgood.com/immortalized-mouse-leptin-receptor-deficient-macrophage-cells-db-1.html |
The Immortalized Mouse Leptin Receptor-deficient Macrophage Cells (DB-1) are non-transformed cells derived from leptin-receptor (LepR) deficient mice which display some phenotypic and functional properties similar to primary macrophages. The cells are characterized as early differentiated macrophages since the high expression of MAC-2, and low expression of F4/80, Ly6G and Ly6C were observed; but CD11b expression was absent. It is recommended for use in studies involving the role of the leptin receptor, susceptibility to infections, innate immune functions, and obesity.
