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Imunoanalýza
Immortalized MS-/- Mouse Alveolar Macrophage Cells (ZK1)
| Unit |
1×10⁶ cells / 1.0 ml |
|---|---|
| Cell Type |
Immortalized Cells |
| Tissue Type |
Brain |
| Organism |
Mouse (M. musculus) |
| Donor History |
MARCO⁻ᐟ⁻ SR-AI/II⁻ᐟ⁻ (MS⁻ᐟ⁻ ) |
| Growth Properties |
Suspension ,round or polygonal |
| Growth Conditions | |
| Immortalization Method |
Infected with J2 retrovirus supernatants collected from the AMJ2-C11 cell line which carries the vraf and vmyc oncogenes |
| Full Information |
https://www.abmgood.com/immortalized-ms-lt-sup-gt-lt-sup-gt-mouse-alveolar-macrophage-cells-zk1.html |
Alveolar macrophages were isolated from the brochoalveolar lavage fluid of MARCO-/- SR-AI/II-/- (MS-/- ) mice and were immortalized with the J2 retrovirus to establish the Immortalized MS-/- Mouse Alveolar Macrophage Cells (ZK1). ZK1 cells exhibit the macrophage morphology, functional activity, and the ability to bind to and ingest particles are reduced due to the deficiency in MARCO and SR-AI/II scavenger receptors. It is a valuable tool to study the functions of MARCO and SR-AI/II scavenger receptors and particle toxicity.abm also have available the ZK2 (T0677) and ZK6 (T0678)clones established from limiting dilution. PCR genotyping was used to determine the deficiency of MARCO and SR-AI/II.
