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Imunoanalýza
Immortalized Ovarian Surface Epithelial Cells (iMOSEC)
| Unit |
1×10⁶ cells / 1.0 ml |
|---|---|
| Cell Type |
Immortalized Cells |
| Tissue Type |
Ovary |
| Organism |
Mouse (M. musculus) |
| Donor History |
11-week-old adult female C57B/6 mouse |
| Growth Properties |
Adherent ,cuboidal |
| Growth Conditions | |
| Immortalization Method |
Serial passaging and electroporation transfection with linearized DNA of E1A and p53DD |
| Full Information |
https://www.abmgood.com/immortalized-ovarian-surface-epithelial-cells-imosec.html |
The Immortalized Ovarian Surface Epithelial Cells (iMOSEC) is derived by co-expression of adenovirus E1A and dominant-negative p53 (p53DD). In addition to its non-tumorigenicity, this cell line maintains its primary phenotype and expresses epithelial-specific markers such as E-cadherin, cytokeratin 8 and 18. This cell line is a useful model for studying ovary growth regulation. Western blot was used to confirm the presence of E1A and p53DD gene and tissue-specific markers.
