Genetika člověka
Mikrobiologické aplikace
NGS
Rapid testy
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Pipetovací špičky
Plasty pro buněčnou kultivaci
Systém pro dlouhodobé skladování vzorků
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PCR, qPCR, RT
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Reverzní transkripce
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Veterinární imunologie
Alergie u zvířat
Intolerance u zvířat
Biochemie
Imunoanalýza
Beta-TC-6 Cells
| Unit |
1×10⁶ cells / 1.0 ml |
|---|---|
| Cell Type |
Tumor Cells |
| Tissue Type |
Pancreas |
| Organism |
Mouse (M. musculus) |
| Donor History |
Insulinoma |
| Growth Properties |
Adherent，Epithelial-like |
| Growth Conditions |
PriCoat™ T25 Flasks (G299) or Applied Cell Extracellular Matrix (G422) are recommended for optimal cell culture. Dulbecco's Modified Eagle Medium (DMEM) ,High Glucose (TM500) + 15% Heat-inactivated FBS + 1% Penicillin/Streptomycin Solution (G255) ,37.0°C ,5% CO₂. |
| Immortalization Method |
Tumor Cell Line |
| Full Information |
Beta-TC-6 cells are an essential mouse pancreatic beta cell line utilized extensively in diabetes research, derived from insulinomas. These cells are capable of synthesizing and secreting insulin in response to glucose, making them a valuable model for investigating insulin regulation and the pathophysiology of diabetes. They are particularly useful for studying insulin secretion mechanisms, glucose homeostasis, and beta cell function. Beta-TC-6 cells can be genetically modified, enhancing research into gene effects on beta cell dynamics and enabling exploration into the pathogenesis of type 1 and type 2 diabetes, as well as testing potential therapeutic agents. Additionally, their responsiveness to various pharmacological stimuli makes them suitable for evaluating the impact of new drugs on insulin secretion and overall beta cell health, contributing significantly to the development of diabetes treatments and understanding beta cell survival and regeneration.
