JAR Cells

Unit

3 x 10^6 cells/ml

Cell Type

Tumor Cells

Tissue Type

Reproductive system cancer cell lines

Organism

Human

Donor History

Choriocarcinoma

Growth Properties

Adherent

Growth Conditions

Culture medium: DMEM:Ham's F12 (1:1)

,

w: 3.1 g/L Glucose

,

w: 2.5 mM L-Glutamine

,

w: 15 mM HEPES

,

w: 0.5 mM Sodium pyruvate

,

w: 1.2 g/L NaHCO3 (Cytion article number 820400a). Supplements: Supplement the medium with 10% FBS. Dissociation reagent: Accutase. Seeding density: 1 x 10⁴ cells/cm². Freeze medium: As a cryopreservation medium

,

we use complete growth medium (including FBS) + 10% DMSO for adequate post-thaw viability

,

or CM-1 (Cytion catalog number 800100)

,

which includes optimized osmoprotectants and metabolic stabilizers to enhance recovery and reduce cryo-induced stress. Incubation atmosphere: 37°C

,

5% CO2

,

humidified atmosphere.

Immortalization Method
Full Information

https://www.cytion.com/JAR-Cells/300221

SKU: 300221 Kategorie: ,
Mgr. Otakar Fišer
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Mgr. Otakar Fišer
Produktový manažer - Life Science
Popis

The JAR cell line is a human choriocarcinoma cell line derived from trophoblastic cells of placental origin. This cell line is widely utilized in cancer research, particularly in studies related to gestational trophoblastic diseases and placental development. JAR cells exhibit characteristics typical of choriocarcinoma, including high levels of human chorionic gonadotropin (hCG) production, which makes them a valuable model for studying hormone regulation, placental biology, and the mechanisms underlying trophoblastic tumorigenesis.

JAR cells are known for their invasive properties and ability to proliferate rapidly, which mirrors the aggressive nature of choriocarcinomas in vivo. These cells are also used to investigate the interaction between trophoblastic cells and the maternal immune system, providing insights into immune evasion mechanisms. Additionally, JAR cells have been employed in studies of drug resistance and chemosensitivity, aiding in the development of therapeutic strategies against trophoblastic cancers. As a cell line derived from human tumors, JAR cells are strictly for in vitro research and are not suitable for any in vivo or therapeutic applications.

O značce

Společnost Cytion vznikla v roce 2004 v německém Heidelbergu s jasným vědeckým posláním: dodávat ověřené lidské a zvířecí buněčné linie bez kontaminace, připravené za přísně kontrolovaných laboratorních podmínek.

Postupně se vypracovala ve spolehlivou buněčnou banku, která slouží akademickým laboratořím, biotechnologickým firmám i farmaceutickým výzkumným týmům po celém světě. Klade přitom důraz na reprodukovatelnost výsledků, přísnou kontrolu kvality a dlouhodobá partnerství.