Genetika člověka
Mikrobiologické aplikace
NGS
Rapid testy
PCR plasty
Pipetovací špičky
Plasty pro buněčnou kultivaci
Systém pro dlouhodobé skladování vzorků
Zkumavky
Třepačky
Suché lázně
Centrifugy
End Point cyclery
Real-time PCR cyclery
Fluorometry
Spektrofotometry
Izolátory nukleových kyselin
Pipetovací roboty
Biobanking
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Jednokanálové
Multikanálové
Sérologické pipety
Jednorázové pipety
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PCR, qPCR, RT
Detekce Mycoplasmat
Reverzní transkripce
Alergie
Intolerance
Elisa
Imunologické analyzátory
Veterinární imunologie
Alergie u zvířat
Intolerance u zvířat
Biochemie
Imunoanalýza
Mouse Oral Carcinoma Cell Line (MOC-L3)
| Unit |
1×10⁶ cells / 1.0 ml |
|---|---|
| Cell Type |
Tumor Cells |
| Tissue Type |
Tongue |
| Organism |
Mouse (M. musculus) |
| Donor History |
C57BL/6 mouse ,tongue tumors |
| Growth Properties |
Adherent; polygonal ,ovoid ,or spindle-shaped |
| Growth Conditions |
Use of PriCoat™ T25 Flasks (G299) or Applied Cell Extracellular Matrix (G422) is required for cell adhesion to the culture vessels. PriGrow III (TM003) + 10% FBS + 1% Penicillin/Streptomycin Solution (G255) ,37.0°C ,5% CO₂. |
| Immortalization Method |
Tumor Cell Line |
| Full Information |
https://www.abmgood.com/mouse-oral-carcinoma-cell-line-moc-l3.html |
Oral squamous cell carcinoma (OSCC) was induced in mice using 4NQO. This cell line shows green fluoresence and expresses a range of epithelial markers. MOC-L3 carries a missense mutation in the DNA binding domains of p53 gene. Western blot, qPCR and IHC were used for epithelium expression, GFP tag, EMT and stemness markers, as well as to confirm the murine nature of the cells. As these cell lines are derived from C57BL/6 mice, they are useful for studies investigating OSCC cells with other genetically modified cells, as well as, OSCC pathogenesis.
