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Imunoanalýza
Mutant Connexin50 Stably Expressing HeLa Cell Line (Cx50S258F)
| Unit |
1×10⁶ cells / 1.0 ml |
|---|---|
| Cell Type |
Stable (KO/Expressing) Cells |
| Tissue Type |
Cervix |
| Organism |
Human (H. sapiens) |
| Donor History |
Female ,31 ,African American ,Cervial cancer |
| Growth Properties |
Adherent ,epithelial-like |
| Growth Conditions |
PriCoat™ T25 Flasks (G299) or Applied Cell Extracellular Matrix (G422) are recommended for optimal cell culture. MEM α ,No Nucleosides Medium (TM512) + 10% Heat-inactivated FBS + 2 mM L-Glutamine (G275) + 1X Non-Essential Amino Acids (TM068) + 1% Penicillin/Streptomycin Solution (G255) ,37.0°C ,5% CO₂. |
| Immortalization Method | |
| Full Information |
This cell line (Cat. T3423) harbors a specific mutation (S258F) in the connexin50 protein, which is implicated in cataract formation. The main characteristic of this mutation is its potential role in altering gap junction communication, leading to aberrant cell signaling and homeostasis. Research applications may include studying the molecular pathways leading to cataractogenesis, investigating connexin50’s role in cell communication, and screening for potential therapeutic interventions.Additional Cell Lines from this panel: Cat. T3424 – Mutant Connexin50 Stably Expressing HeLa Cell Line (Cx50S259Y)
