Genetika člověka
Mikrobiologické aplikace
NGS
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Plasty pro buněčnou kultivaci
Systém pro dlouhodobé skladování vzorků
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Veterinární imunologie
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Intolerance u zvířat
Biochemie
Imunoanalýza
sNF94.3 Cells
| Unit |
1×10⁶ cells / 1.0 ml |
|---|---|
| Cell Type |
Tumor Cells |
| Tissue Type |
Nerve |
| Organism |
Human (H. sapiens) |
| Donor History |
Female ,43 ,Neurofibromatosis type 1 tumor |
| Growth Properties |
Adherent ,spindle-shaped |
| Growth Conditions |
PriCoat™ T25 Flasks (G299) or Applied Cell Extracellular Matrix (G422) are recommended for optimal cell culture. Dulbecco's Modified Eagle Medium (DMEM) ,High Glucose (TM500) + 10% Heat-inactivated FBS + 1% Penicillin/Streptomycin Solution (G255) ,37.0°C ,5% CO₂. |
| Immortalization Method |
Tumor Cell Line |
| Full Information |
sNF94.3 cells were derived from a neurofibromatosis type 1 tumor of a female human, a human schwann cell-like cell line. Intraneurolal injection of this cell line established a successful and slow growing tumor, which disrupted the host nerve. There is a high physical and histological resemblance between this cell line and plexiform neurofibromas. This model may be used for further investigation of plexiform neurofibroma tumorigenesis and relevant therapeutic treatment for this malignancy.
