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Immortalized Mouse Prolactin-Responsive Mammary Epithelial Cells (HC11)
| Unit |
1×10⁶ cells / 1.0 ml |
|---|---|
| Cell Type |
Immortalized Cells |
| Tissue Type |
Mammary |
| Organism |
Mouse (M. musculus) |
| Donor History |
Heterogeneous COMMA-1D mouse |
| Growth Properties |
Adherent ,cuboidal |
| Growth Conditions | |
| Immortalization Method |
Transfection with pY3 plasmid |
| Full Information |
https://www.abmgood.com/immortalized-mouse-prolactin-responsive-mammary-epithelial-cells-hc11.html |
The Immortalized Mouse Prolactin-Responsive Mammary Epithelial Cells (HC11) was isolated from a subpopulation of cells in the heterogeneous COMMA-1D mouse mammary epithelial cell. The subpopulation was isolated based on its 4-fold higher β-casein milk protein production after lactogenic hormone induction with dexamethasone, insulin and prolactin in comparison to parental population of COMMA-1D cells. The Immortalized Mouse Prolactin-Responsive Mammary Epithelial Cells are applicable in studies related to prolactin-regulated genes.
