EB1 Cells

The EB1 cell line is a human-derived cell line established from biopsy fragments and cell clumps of Burkitt lymphoma. This line was originally cultivated in Eagle’s basal medium supplemented with 10% human serum. The unique growth conditions facilitated the development of cells that predominantly grew as free-floating single individuals or doublets. The EB1 cells exhibit a characteristic doubling time of approximately 48 hours, highlighting their rapid proliferation rate, which is a hallmark feature of lymphoblasts.

Morphologically, the EB1 cells display uniform altered lymphoblast characteristics, indicating their derivation from lymphoid tissue. The cell line has been utilized extensively in the study of Burkitt’s lymphoma, providing insights into the pathology of lymphoid malignancies. It serves as a valuable model for researching the biological behavior of lymphoid cells under various experimental conditions, aiding in the exploration of therapeutic targets and the understanding of lymphoma progression.