Genetika člověka
Mikrobiologické aplikace
NGS
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PCR plasty
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Plasty pro buněčnou kultivaci
Systém pro dlouhodobé skladování vzorků
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Izolátory nukleových kyselin
Pipetovací roboty
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Jednokanálové
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Alergie
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Imunologické analyzátory
Veterinární imunologie
Alergie u zvířat
Intolerance u zvířat
Biochemie
Imunoanalýza
FR37-CMT Cells
| Unit |
1×10⁶ cells / 1.0 ml |
|---|---|
| Cell Type |
Tumor Cells |
| Tissue Type |
Mammary |
| Organism |
Dog (Canine) |
| Donor History |
Female |
| Growth Properties |
Adherent ,stellate shaped |
| Growth Conditions |
Use of PriCoat™ T25 Flasks (G299) or Applied Cell Extracellular Matrix (G422) is required for cell adhesion to the culture vessels. PriGrow III (TM003) + 10% heat-inactivated FBS + 1% Penicillin/Streptomycin Solution (G255) ,37.0°C ,5% CO₂ |
| Immortalization Method |
Tumor Cell Line |
| Full Information |
FR37-CMT Cells are isolated from female dogs undergoing biopsies for mammary tumors. The cells are tumorigenic and have the loss of contact inhibition. FR37-CMT cells express cancer-related genes such as ESR1, ERBB2, and PGR. Additionally, genes related to the epithelial to mesenchymal transition (EMT) process such as the gain of vimentin and the loss of E-cadherin. They are capable of proliferating in vitro for a consistent source of cells for research development in canine mammary tumor (CMT) biology. It is a valuable tool for future developments in therapies targeted towards CMT.
