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Imunoanalýza
Immortalized Human Corneal Keratinocytes (IHCK)
| Unit |
1×10⁶ cells / 1.0 ml |
|---|---|
| Cell Type |
Immortalized Cells |
| Tissue Type |
Eye |
| Organism |
Human (H. sapiens) |
| Donor History |
Not disclosed |
| Growth Properties |
Adherent ,spindle-shaped |
| Growth Conditions | |
| Immortalization Method |
Serial passaging and transduction with retroviruses carrying human papillomavirus type 16 E6/E7 gene. |
| Full Information |
https://www.abmgood.com/immortalized-human-corneal-keratinocytes-ihck.html |
Corneal Keratinocytes play a major role in maintaining the balance of stromal substances and preserving the corneal transparency. Established using the HPV16 E6/E7 genes, The Immortalized Human Corneal Keratinocytes (IHCK) not only retain their authentic cell biomarkers (CK12, CK19), but also displays fairly disomic cytogenetic status at chromosomes 1, 8, 10 and 18, which is an indication of normal diploid chromosomal status. Together with the Immortalized Human Corneal Stromal Fibroblasts (T0578) and the Immortalized Human Corneal Endothelial Cells (T0577) – isolated from the same donor and immortalized using the same platform – this uniform model system presents a valuable tool for studies involving cornea homeostasis and ophthalmologic diseases.
