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Immortalized Human Neonatal Foreskin Keratinocytes (HKc16E6/E7-II)
| Unit |
1×10⁶ cells / 1.0 ml |
|---|---|
| Cell Type |
Immortalized Cells |
| Tissue Type |
Skin |
| Organism |
Human (H. sapiens) |
| Donor History |
Not disclosed |
| Growth Properties |
Adherent ,epithelial-like |
| Growth Conditions | |
| Immortalization Method |
Transfection with HPV16 E6 and E7 |
| Full Information |
https://www.abmgood.com/immortalized-human-neonatal-foreskin-keratinocytes-hkc16e6-e7-ii.html |
Immortalized Human Neonatal Foreskin Keratinocytes (HKc16E6/E7-II) are normal human keratinocytes isolated from neonatal foreskins biopsy and immortalized by transfection with HPV16 E6 and E7 genes. HKc16E6/E7-II cells will be useful for investigating the molecular biology of HPV16 and the interactions between the viral DNA and the human genome. HKc16E6/E7-II cell line can also serve a model for analyzing the effects of HPV16 on the function and pathology of human epithelial cells. Characterization by RNaseH assays, ODN uptake measurements, Western blot, and RT-PCR.
