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Immortalized Mouse Floxed Fam20c Osteoblast Cells
| Unit |
1×10⁶ cells / 1.0 ml |
|---|---|
| Cell Type |
Immortalized Cells |
| Tissue Type |
Bone |
| Organism |
Mouse (M. musculus) |
| Donor History |
Postnatal 1 Day Fam20cf/f Mice |
| Growth Properties |
Adherent ,polygonal |
| Growth Conditions | |
| Immortalization Method |
Serial passaging and transduction with recombinant lentiviruses carrying SV40 Large T antigen |
| Full Information |
https://www.abmgood.com/immortalized-mouse-floxed-fam20c-osteoblast-cells.html |
Immortalized Mouse Floxed Fam20c Osteoblast Cells are a reliable tool to study osteoblasts and the roles in formation, mineralization and repair of the osteoblasts. They carry the floxed Fam20c allele which allows further manipulation on exon 6-9 by Cre recombinase to obtain null Fam20c allele cells. Fam20c expresses the FAM20C kinase which has been associated with bone-related diseases due to mineralization dysfunction. The Immortalized Mouse Floxed Fam20c Osteoblast Cells can be expanded in vitro for research on the field of mineralization disorders.
