KCNN4 CRISPR Knockout KPCY Cell Line – AI119

This cell line features a stable knockout of the mouse KCNN4 gene using CRISPR/Cas9 technology. KCNN4 encodes a potassium channel protein, which is important for controlling the flow of potassium ions across the cell membrane. This channel is particularly significant in various cellular processes including cell proliferation, migration, and volume regulation.The knockout of KCNN4 in this cell line allows researchers to study the role of this potassium channel in cell function and disease processes, particularly in the context from which these cells were derived. Studies might focus on how altering KCNN4 activity affects cancer cell behavior, including tumorigenesis, metastasis, and response to treatments.