MA-891 Cells

Unit

3 x 10^6 cells/ml

Cell Type

Tumor Cells

Tissue Type

Mouse cell lines

Organism

Mouse

Donor History

Carcinoma

Growth Properties

Adherent

Growth Conditions

Culture medium: RPMI-1640 with 10% FBS; 1% Penicillin-Streptomycin Solution. Supplements: Supplement the medium with 10% FBS and 1% Penicillin-Streptomycin. Dissociation reagent: Accutase. Seeding density: 1 to 3 × 10⁴ cells/cm². Freeze medium: As a cryopreservation medium

,

we use complete growth medium (including FBS) + 10% DMSO for adequate post-thaw viability

,

or CM-1 (Cytion catalog number 800100)

,

which includes optimized osmoprotectants and metabolic stabilizers to enhance recovery and reduce cryo-induced stress. Incubation atmosphere: 37°C

,

5% CO2

,

humidified atmosphere.

Immortalization Method
Full Information

https://www.cytion.com/MA-891-Cells/305581

SKU: 305581 Kategorie: ,
Mgr. Otakar Fišer
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Mgr. Otakar Fišer
Produktový manažer - Life Science
Popis

MA-891 is a highly metastatic murine mammary gland carcinoma cell line, established from a spontaneous mammary tumor in a mouse and selected for its aggressive metastatic behavior. The line grows as an adherent monolayer and is classified as a syngeneic tumor cell line compatible with immunocompetent mouse hosts, enabling in vivo studies of mammary carcinoma growth, metastasis, and immune interaction. MA-891 represents a highly metastatic variant selected for its propensity to disseminate to distant organs, particularly the lungs.
MA-891 is applicable in murine mammary carcinoma research including studies of metastatic cascade biology, invasion, angiogenesis, tumor-immune interactions, and preclinical evaluation of anti-metastatic and anti-tumor agents. Its syngeneic origin enables testing of immunotherapy approaches in immunocompetent hosts, including checkpoint inhibitor evaluation and cancer vaccine development. The high metastatic potential makes it a useful model for studying metastasis prevention strategies and the biology of aggressive mammary carcinoma.

O značce

Společnost Cytion vznikla v roce 2004 v německém Heidelbergu s jasným vědeckým posláním: dodávat ověřené lidské a zvířecí buněčné linie bez kontaminace, připravené za přísně kontrolovaných laboratorních podmínek.

Postupně se vypracovala ve spolehlivou buněčnou banku, která slouží akademickým laboratořím, biotechnologickým firmám i farmaceutickým výzkumným týmům po celém světě. Klade přitom důraz na reprodukovatelnost výsledků, přísnou kontrolu kvality a dlouhodobá partnerství.