MDCC-MSB1 Cells

Unit

5 x 10^6 cells/ml

Cell Type

Tumor Cells

Tissue Type

Avian cell lines

Organism

Chicken

Donor History

Marek disease

Growth Properties

Suspension

Growth Conditions

Culture medium: RPMI 1640

,

w: 2.0 mM stable Glutamine

,

w: 2.0 g/L NaHCO3 (Cytion article number 820700a). Supplements: Supplement the medium with 10% FBS. Seeding density: 1 x 10⁶ cells/ml. Freeze medium: As a cryopreservation medium

,

we use complete growth medium (including FBS) + 10% DMSO for adequate post-thaw viability

,

or CM-1 (Cytion catalog number 800100)

,

which includes optimized osmoprotectants and metabolic stabilizers to enhance recovery and reduce cryo-induced stress. Incubation atmosphere: 37°C

,

5% CO2

,

humidified atmosphere.

Immortalization Method
Full Information

https://www.cytion.com/MDCC-MSB1-Cells/601413

SKU: 601413 Kategorie: ,
Mgr. Otakar Fišer
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Mgr. Otakar Fišer
Produktový manažer - Life Science
Popis

The MDCC-MSB1 cell line is a lymphoblastoid cell line derived from a chicken with Marek’s disease, a highly contagious viral disease caused by Marek’s disease virus (MDV), which belongs to the herpesvirus family. These cells are extensively used in veterinary virology and immunology research to study the pathogenesis of MDV, as well as in the development and evaluation of vaccines against this disease. The MDCC-MSB1 cell line exhibits characteristics typical of lymphoid cells, such as the expression of specific surface markers and cytokine production, which are crucial for understanding the immune response to MDV infection.

In addition to its role in MDV research, the MDCC-MSB1 cell line is valuable for studying general mechanisms of oncogenesis and viral replication in avian species. The cells are known for their robust growth in suspension culture, making them convenient for large-scale production and experimental manipulation. Researchers utilize this cell line to investigate the molecular interactions between MDV and its host, to identify viral and host factors involved in disease progression, and to screen potential antiviral compounds. Overall, the MDCC-MSB1 cell line is a vital tool in both basic and applied avian virology research.

O značce

Společnost Cytion vznikla v roce 2004 v německém Heidelbergu s jasným vědeckým posláním: dodávat ověřené lidské a zvířecí buněčné linie bez kontaminace, připravené za přísně kontrolovaných laboratorních podmínek.

Postupně se vypracovala ve spolehlivou buněčnou banku, která slouží akademickým laboratořím, biotechnologickým firmám i farmaceutickým výzkumným týmům po celém světě. Klade přitom důraz na reprodukovatelnost výsledků, přísnou kontrolu kvality a dlouhodobá partnerství.