MH-S Cells

Unit

3 x 10^6 cells/ml

Cell Type

Immortalized Cells

Tissue Type

Mouse cell lines

Organism

Mouse

Donor History
Growth Properties

Adherent/suspension

Growth Conditions

Culture medium: RPMI 1640

,

w: 2.0 mM stable Glutamine

,

w: 2.0 g/L NaHCO3 (Cytion article number 820700a). Supplements: Supplement the medium with 10% FBS. Dissociation reagent: Accutase. Freeze medium: As a cryopreservation medium

,

we use complete growth medium (including FBS) + 10% DMSO for adequate post-thaw viability

,

or CM-1 (Cytion catalog number 800100)

,

which includes optimized osmoprotectants and metabolic stabilizers to enhance recovery and reduce cryo-induced stress. Incubation atmosphere: 37°C

,

5% CO2

,

humidified atmosphere.

Immortalization Method
Full Information

https://www.cytion.com/MH-S-Cells/300487

SKU: 300487 Kategorie: ,
Mgr. Otakar Fišer
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Mgr. Otakar Fišer
Produktový manažer - Life Science
Popis

MH-S is a murine alveolar macrophage cell line derived from adult mice. These cells are widely used in immunological research due to their robust phagocytic activity and their ability to produce a variety of cytokines in response to pathogenic stimuli. As an alveolar macrophage model, MH-S cells are particularly valuable in studying pulmonary immune responses, lung inflammation, and respiratory infections. Their ability to mimic the behavior of primary alveolar macrophages makes them an indispensable tool for understanding the mechanisms of host defense in the respiratory tract.

MH-S cells are also instrumental in the study of macrophage biology and function. They are employed to investigate macrophage activation, differentiation, and the signaling pathways involved in immune responses. Researchers utilize this cell line to explore the interactions between macrophages and pathogens, including bacteria, viruses, and fungi. Additionally, MH-S cells serve as a model to examine the effects of various pharmacological agents on macrophage activity, offering insights into potential therapeutic approaches for respiratory diseases.

O značce

Společnost Cytion vznikla v roce 2004 v německém Heidelbergu s jasným vědeckým posláním: dodávat ověřené lidské a zvířecí buněčné linie bez kontaminace, připravené za přísně kontrolovaných laboratorních podmínek.

Postupně se vypracovala ve spolehlivou buněčnou banku, která slouží akademickým laboratořím, biotechnologickým firmám i farmaceutickým výzkumným týmům po celém světě. Klade přitom důraz na reprodukovatelnost výsledků, přísnou kontrolu kvality a dlouhodobá partnerství.