RCC-KL Cells

Unit

3 x 10^6 cells/ml

Cell Type

Tumor Cells

Tissue Type

Kidney cancer cell lines

Organism

Human

Donor History

Clear cell renal cell carcinoma

Growth Properties

Monolayer

,

adherent

Growth Conditions

Culture medium: RPMI 1640

,

w: 2.0 mM stable Glutamine

,

w: 2.0 g/L NaHCO3 (Cytion article number 820700a). Supplements: Supplement the medium with 10% FBS. Dissociation reagent: Accutase. Freeze medium: As a cryopreservation medium

,

we use complete growth medium (including FBS) + 10% DMSO for adequate post-thaw viability

,

or CM-1 (Cytion catalog number 800100)

,

which includes optimized osmoprotectants and metabolic stabilizers to enhance recovery and reduce cryo-induced stress. Incubation atmosphere: 37°C

,

5% CO2

,

humidified atmosphere.

Immortalization Method
Full Information

https://www.cytion.com/RCC-KL-Cells/300281

SKU: 300281 Kategorie: ,
Mgr. Otakar Fišer
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Mgr. Otakar Fišer
Produktový manažer - Life Science
Popis

The RCC-KL cell line is derived from renal cell carcinoma (RCC), a common type of kidney cancer that typically arises from the epithelial cells of the kidney’s proximal tubules. RCC-KL is utilized as an in vitro model to study the biological and pathological mechanisms underlying renal cell carcinoma. Researchers commonly employ RCC cell lines like RCC-KL to investigate cancer growth, invasion, and therapeutic responses in the context of kidney cancer. Although detailed genetic information on RCC-KL is limited, renal cell carcinoma models are often used to explore the roles of key pathways involved in cancer progression, including those related to hypoxia, angiogenesis, and immune evasion. As such, RCC-KL may be valuable for studying drug responses and testing novel therapeutic agents, which is critical for developing improved treatments for kidney cancer. Given the complexity of RCC, cell lines like RCC-KL are instrumental in preclinical research focused on understanding drug resistance mechanisms and the interactions between cancer cells and the immune system. However, further characterization and published research are needed to fully elucidate the specific features and applications of RCC-KL in scientific studies.

O značce

Společnost Cytion vznikla v roce 2004 v německém Heidelbergu s jasným vědeckým posláním: dodávat ověřené lidské a zvířecí buněčné linie bez kontaminace, připravené za přísně kontrolovaných laboratorních podmínek.

Postupně se vypracovala ve spolehlivou buněčnou banku, která slouží akademickým laboratořím, biotechnologickým firmám i farmaceutickým výzkumným týmům po celém světě. Klade přitom důraz na reprodukovatelnost výsledků, přísnou kontrolu kvality a dlouhodobá partnerství.