Genetika člověka
Mikrobiologické aplikace
NGS
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PCR plasty
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Jednokanálové
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PCR, qPCR, RT
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Reverzní transkripce
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Imunologické analyzátory
Veterinární imunologie
Alergie u zvířat
Intolerance u zvířat
Biochemie
Imunoanalýza
COS-7-DRA1*01:01/DRB1*11:01 Cell Line
| Unit |
1×10⁶ cells / 1.0 ml |
|---|---|
| Cell Type |
Stable (KO/Expressing) Cells |
| Tissue Type |
Kidney |
| Organism |
Monkey (Primate) |
| Donor History |
Cercopithecus aethiops |
| Growth Properties |
Adherent ,fibroblast |
| Growth Conditions |
PriCoat™ T25 Flasks (G299) or Applied Cell Extracellular Matrix (G422) are recommended for optimal cell culture. Dulbecco's Modified Eagle Medium (DMEM) ,High Glucose (TM500) + 10% FBS + 2 mM L-Glutamine (G275) + 1% Penicillin/Streptomycin Solution (G255) ,37.0°C ,5% CO₂. |
| Immortalization Method | |
| Full Information |
The COS-7-DRA101:01/DRB111:01 cell line expresses the HLA-DRA101:01 and DRB111:01 antigens, which play a critical role in antigen presentation to helper T-cells. Developed via retroviral transduction, this cell line was validated using flow cytometry and is maintained without antibiotics. It is valuable for research into the interactions between HLA class II molecules and the immune system, especially in the context of autoimmune diseases and transplant immunology.
