Genetika člověka
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Intolerance u zvířat
Biochemie
Imunoanalýza
COS-7-DRA1*01:01/DRB1*13:03 Cell Line
| Unit |
1×10⁶ cells / 1.0 ml |
|---|---|
| Cell Type |
Stable (KO/Expressing) Cells |
| Tissue Type |
Kidney |
| Organism |
Monkey (Primate) |
| Donor History |
Cercopithecus aethiops |
| Growth Properties |
Adherent ,fibroblast |
| Growth Conditions |
PriCoat™ T25 Flasks (G299) or Applied Cell Extracellular Matrix (G422) are recommended for optimal cell culture. Dulbecco's Modified Eagle Medium (DMEM) ,High Glucose (TM500) + 10% FBS + 2 mM L-Glutamine (G275) + 1% Penicillin/Streptomycin Solution (G255) ,37.0°C ,5% CO₂. |
| Immortalization Method | |
| Full Information |
The COS-7-DRA101:01/DRB113:03 cell line expresses HLA-DRA101:01 and DRB113:03 antigens, which are essential for antigen presentation to helper T-cells. This cell line, generated through retroviral transduction, was validated using flow cytometry and is maintained without antibiotics. It is ideal for research on immune response dynamics, antigen presentation, and the development of therapies targeting HLA class II molecules in autoimmune diseases.
