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TGFBR2 Stably Over-Expressing C4-B4 Cell Line (C4-2B–RII)
| Unit |
1×10⁶ cells / 1.0 ml |
|---|---|
| Cell Type |
Stable (KO/Expressing) Cells |
| Tissue Type |
Prostate |
| Organism |
Human (H. sapiens) |
| Donor History | |
| Growth Properties |
Adherent ,epithelial-like |
| Growth Conditions |
PriCoat™ ECM T25 Flasks (G999) or Applied Cell Extracellular Matrix (G422) are required for cell adhesion to the culture vessels. RPMI 1640 Medium (TM503) + 10% FBS + 1% Penicillin/Streptomycin Solution (G255) ,37.0°C ,5% CO₂. |
| Immortalization Method | |
| Full Information |
https://www.abmgood.com/TGFBR2-Stably-Over-Expressing-C4-B4-Cell-Line-C4-2B-RII-T3426.html |
C4-2B-RII cells were generated to over-express TGFBR2 (RII) through lentivirally transduction. Overexpression was confirmed through Western blot. This cell line is suitable for prostaste cancer related research. The C4-2B–RII cell line is a valuable tool for researchers studying the TGF-β signaling pathway, particularly in the context of cancer research. Over-expression of TGFBR2 in this cell line allows for the investigation of its role in tumorigenesis, the cellular response to TGF-β, and potential resistance mechanisms to TGF-β-related therapies. This cell line can be utilized in various experimental setups, including drug screening, signal transduction studies, and the exploration of cellular mechanisms underlying metastatic progression.Additional cell lines from this panel: Cat. T3425 – TGFBR2 Stably Over-Expressing LNCaP Cell Line (LNCaP-RII)
