Human IFNAR2 Stable Knockout HeLa Cell Line

Unit

1×10⁶ cells / 1.0 ml

Cell Type

Stable (KO/Expressing) Cells

Tissue Type

Cervix

Organism

Human (H. sapiens)

Donor History

Growth Properties

Adherent

epithelial

Growth Conditions

PriCoat™ T25 Flasks (G299) or Applied Cell Extracellular Matrix (G422) are recommended for optimal cell culture. Dulbecco's Modified Eagle Medium (DMEM)

High Glucose (TM500) + 10% FBS + 1 mM Sodium Pyruvate (TM057) + 1% Penicillin/Streptomycin Solution (G255)

37.0°C

5% CO₂.

Immortalization Method

Full Information

https://www.abmgood.com/Human-IFNAR2-Stable-Knockout-HeLa-Cell-Line-T3981.html

The Human IFNAR2 Stable Knockout HeLa Cell Line (T3981) provides a unique platform for the study of Type I interferon signaling by specifically lacking the IFNAR2 gene. IFNAR2, together with IFNAR1, forms the receptor complex for Type I interferons, initiating a cascade of events leading to immune responses. The absence of IFNAR2 in this cell line eliminates the receptor’s ability to bind interferons, thereby inhibiting subsequent JAK-STAT signaling and gene expression of ISGs. This cell line is particularly valuable for delineating IFNAR2’s specific contributions to the interferon signaling pathway, understanding the redundancy and specificity within the Type I interferon receptor complex, and investigating potential therapeutic avenues in immunology and oncology.Complete list of cell lines from this panel:Cat. T3980 – Human IFNAR1 Stable Knockout HeLa Cell LineCat. T3981 – Human IFNAR2 Stable Knockout HeLa Cell LineCat. T3982 – Human STAT1 Stable Knockout HeLa Cell LineCat. T3983 – Human STAT2 Stable Knockout HeLa Cell Line

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Unit	1×10⁶ cells / 1.0 ml
Cell Type	Stable (KO/Expressing) Cells
Tissue Type	Cervix
Organism	Human (H. sapiens)
Donor History
Growth Properties	Adherent , epithelial
Growth Conditions	PriCoat™ T25 Flasks (G299) or Applied Cell Extracellular Matrix (G422) are recommended for optimal cell culture. Dulbecco's Modified Eagle Medium (DMEM) , High Glucose (TM500) + 10% FBS + 1 mM Sodium Pyruvate (TM057) + 1% Penicillin/Streptomycin Solution (G255) , 37.0°C , 5% CO₂.
Immortalization Method
Full Information	https://www.abmgood.com/Human-IFNAR2-Stable-Knockout-HeLa-Cell-Line-T3981.html

Přidat mezi Oblíbené

Katalogové číslo: T3981 Kategorie: Buněčné linie, Stable (KO/Expression) Cell Lines

Popis
O značce

Popis

O značce

Applied Biological Materials (abm) je jedním z našich klíčových dodavatelů pro biotechnologický průmysl. Společnost byla založena v roce 2004 a již více než deset let podporuje vědecké objevy v oblasti přírodních věd a vývoje léčiv. Její sídlo se nachází ve Vancouveru v Kanadě. ABM je pro nás neocenitelným partnerem zejména v  oblasti dodávek buněčných kultur, genových a virových vektorů, produktů pro molekulární biologii a PCR, nástrojů pro technologie CRISPR a RNAi, protilátek i základních reagencií pro molekulárně genetické procesy.

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