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Human MS4A1 CRISPR Knockout Jurkat Cell Line – T2 AE202
| Unit |
1×10⁶ cells / 1.0 ml |
|---|---|
| Cell Type |
Stable (KO/Expressing) Cells |
| Tissue Type |
Peripheral Blood |
| Organism |
Human (H. sapiens) |
| Donor History |
Male ,14 ,T-cell leukemia |
| Growth Properties |
Suspension ,round |
| Growth Conditions |
PriCoat™ T25 Flasks (G299) are recommended for optimal cell culture. RPMI 1640 Medium (TM503) + 10% FBS + 1% Penicillin/Streptomycin Solution (G255) ,37.0°C ,5% CO₂. |
| Immortalization Method | |
| Full Information |
This cell line (Cat. T3436) features a stable knockout of human MS4A1 mediated by CRISPR/Cas9 gene editing technology. Protein knockout was confimed through western blot. This cell line is useful for for studying the function of the MS4A1 gene, which is involved in B-cell activation and proliferation. The gene is also linked to immunodeficiency common variable type 5 and lymphoma. These cells provide a model for investigating MS4A1’s role in the immune response and related diseases.
